FCGR3A

FCGR3A

ساختارهای موجود

جستجوی هم‌ساخت‌شناسی: PDBe RCSB

فهرست شناسه‌های PDB
3AY4, 3SGJ, 3SGK, 3WN5, 5D6D, 5BW7

معین‌کننده‌ها

نام‌های دیگر

FCGR3A, CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3, IMD20, Fc fragment of IgG receptor IIIa, Fc gamma receptor IIIa, FcGRIIIA, CD16-II

شناسه‌های بیرونی

OMIM: 146740 MGI: 2179523 HomoloGene: 477 GeneCards: FCGR3A

موقعیت ژن (موش)

کروموزوم	کروموزوم ۱ (موش)^[۱]

نوار	1 H3\|1 78.53 cM	شروع	170,846,489 bp^[۱]
نوار	1 H3\|1 78.53 cM	پایان	170,857,330 bp^[۱]

هستی‌شناسی ژن
عملکرد ملکولی	• IgG binding
ترکیبات سلولی	• integral component of membrane • extracellular region • پوسته یاخته • extracellular exosome • external side of plasma membrane • membrane
فرایند زیستی	• GO:0046730، GO:0046737، GO:0046738، GO:0046736 پاسخ ایمنی • Fc-gamma receptor signaling pathway involved in phagocytosis • regulation of immune response
منابع: آمیگو / کوئیک‌گو

هم‌ساخت‌شناسی

گونه‌ها

انسان

موش


2214


246256


ENSG00000203747


ENSMUSG00000059089

یونی‌پروت


P08637


A0A0B4J1G0

RefSeq (mRNA)


NM_001127592، NM_001127593، NM_001127595، NM_001127596، NM_001329120، NM_001329122، NM_001386450، XM_047449443، XM_047449444 NM_000569، NM_001127592، NM_001127593، NM_001127595، NM_001127596، NM_001329120، NM_001329122، NM_001386450، XM_047449443، XM_047449444


NM_180961 NM_144559، NM_180961

RefSeq (پروتئین)


NP_001121064، NP_001121065، NP_001121067، NP_001121068، NP_001316049، NP_001316051، XP_024309832 NP_000560، NP_001121064، NP_001121065، NP_001121067، NP_001121068، NP_001316049، NP_001316051، XP_024309832


NP_653142

موقعیت (UCSC)

ن/م

Chr : 170.85 – 170.86 Mb

جستجوی PubMed

^[۲]

^[۳]

ویکی‌داده

مشاهده/ویرایش انسان

مشاهده/ویرایش موش

گیرندهٔ III-A بخش Fc پادتن جی با میل ترکیبی کم (انگلیسی: Low affinity immunoglobulin gamma Fc region receptor III-A) که با نام‌های اختصاری «FCGR3A» و «CD16a» هم شناخته می‌شود، پروتئینی است که در انسان توسط ژن «FCGR3A» کُد می‌شود.^[۴]^[۵]

مشخص شده‌است که CD16a جزئی از مجموعه تمایزی بر سطح سلول‌هاست.

منابع

1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000059089 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Qiu WQ, de Bruin D, Brownstein BH, Pearse R, Ravetch JV (May 1990). "Organization of the human and mouse low-affinity Fc gamma R genes: duplication and recombination". Science. 248 (4956): 732–5. doi:10.1126/science.2139735. PMID 2139735.
↑ "Entrez Gene: FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)".

مشارکت‌کنندگان ویکی‌پدیا. «FCGR3A». در دانشنامهٔ ویکی‌پدیای انگلیسی، بازبینی‌شده در ۱۸ دسامبر ۲۰۱۷.

بیشتر بخوانید

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نگارخانه PDB

1e4j: CRYSTAL STRUCTURE OF THE SOLUBLE HUMAN FC-GAMMA RECEPTOR III
1e4k: CRYSTAL STRUCTURE OF SOLUBLE HUMAN IGG1 FC FRAGMENT-FC-GAMMA RECEPTOR III COMPLEX
1fnl: CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF A HUMAN FCGRIII
1t83: CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (ORTHORHOMBIC)
1t89: CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (HEXAGONAL)