| FCGR3B |
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| معینکنندهها |
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| نامهای دیگر | FCGR3B, CD16, CD16b, FCG3, FCGR3, FCR-10, FCRIII, FCRIIIb, Fc fragment of IgG receptor IIIb, CD16A, FCGR3A, Fc gamma receptor IIIb, CD16-I |
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| شناسههای بیرونی | OMIM: 610665 MGI: 2179523 HomoloGene: 477 GeneCards: FCGR3B |
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| همساختشناسی |
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| گونهها | انسان | موش |
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| Entrez | | |
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| آنسامبل | | |
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| یونیپروت | | |
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| RefSeq (mRNA) | | |
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| RefSeq (پروتئین) | | |
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| موقعیت (UCSC) | ن/م | Chr : 170.85 – 170.86 Mb |
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| جستجوی PubMed | [۲] | [۳] |
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| ویکیداده |
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گیرندهٔ III-B بخش Fc پادتن جی با میل ترکیبی کم (انگلیسی: Low affinity immunoglobulin gamma Fc region receptor III-B) که با نامهای اختصاری «FCGR3B» و «CD16b» هم شناخته میشود، نام یک پروتئین است که در انسان توسط ژنی به همین نام کُد میشود.[۴]
جهش و تنوع تعداد کپی در این ژن با برخی موارد بالینی گلومرولونفریت مرتبط است.[۵]
منابع
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000059089 - Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Entrez Gene: FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)".
- ↑ Aitman TJ, Dong R, Vyse TJ, Norsworthy PJ, Johnson MD, Smith J, Mangion J, Roberton-Lowe C, Marshall AJ, Petretto E, Hodges MD, Bhangal G, Patel SG, Sheehan-Rooney K, Duda M, Cook PR, Evans DJ, Domin J, Flint J, Boyle JJ, Pusey CD, Cook HT (Feb 2006). "Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans". Nature. 439 (7078): 851–5. doi:10.1038/nature04489. PMID 16482158.
بیشتر بخوانید
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- Siriboonrit U, Tsuchiya N, Sirikong M, Kyogoku C, Bejrachandra S, Suthipinittharm P, Luangtrakool K, Srinak D, Thongpradit R, Fujiwara K, Chandanayingyong D, Tokunaga K (May 2003). "Association of Fcgamma receptor IIb and IIIb polymorphisms with susceptibility to systemic lupus erythematosus in Thais". Tissue Antigens. 61 (5): 374–83. doi:10.1034/j.1399-0039.2003.00047.x. PMID 12753656.
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نگارخانه PDB |
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1e4j: CRYSTAL STRUCTURE OF THE SOLUBLE HUMAN FC-GAMMA RECEPTOR III 1e4k: CRYSTAL STRUCTURE OF SOLUBLE HUMAN IGG1 FC FRAGMENT-FC-GAMMA RECEPTOR III COMPLEX 1fnl: CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF A HUMAN FCGRIII 1t83: CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (ORTHORHOMBIC) 1t89: CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (HEXAGONAL) |
