آلفا-اتیل‌تریپتامین

آلفا-اتیل‌تریپتامین
داده‌های بالینی
نام‌های دیگر	۳-(۲-آمینوبوتیل)ایندول
کد ATC	None;
وضعیت قانونی
وضعیت قانونی	CA: رده سه ; UK: کلاس آ ; US: رده یک ;
شناسه‌ها
	نام آیوپاک 1-(1H-indol-3-yl)butan-2-amine;
شمارهٔ سی‌ای‌اس	2235-90-7 118-68-3;
پاب‌کم CID	8367;
دراگ‌بنک	DB01546 ;
کم‌اسپایدر	8064 ;
UNII	GR181O3R32;
CompTox Dashboard (EPA)	DTXSID1046764 ;
داده‌های فیزیکی و شیمیایی
فرمول شیمیایی	C12H16N2
جرم مولی	۱۸۸٫۲۷۴ g·mol−1
مدل سه بعدی (جی‌مول)	Interactive image;
نقطه ذوب	۲۲۲ تا
	SMILES c1cccc2c1c(c[nH]2)CC(N)CC;
	InChI InChI=1S/C12H16N2/c1-2-10(13)7-9-8-14-12-6-4-3-5-11(9)12/h3-6,8,10,14H,2,7,13H2,1H3 ; Key:ZXUMUPVQYAFTLF-UHFFFAOYSA-N ;
	(صحت‌سنجی)

آلفا-اتیل‌تریپتامین (αET ,AET)، همچنین به عنوان اتریپتامین (INN ,BAN ,USAN) نیز شناخته می‌شود، یک داروی روان‌گردان، محرک و entactogenic از دسته تریپتامین‌ها است.^[۱]^[۲] این ماده در اصل به عنوان داروی ضد افسردگی با نام تجاری Monase توسط Upjohn در دهه ۱۹۶۰ تولید و به بازار عرضه شد.^[۳]

منابع

↑ ""Erowid AET (alpha-ethyltryptamine) Vault"".
↑ Alexander Shulgin; Ann Shulgin. "#11, a-ET: Alpha-Ethyltryptamine; Indole,3-(2-Aminobutyl); Tryptamine,Alpha-Ethyl; 3-(2-Aminobutyl)Indole; Monase,". "Tryptamines i Have Known And Loved: The Continuation", Part 2, "The Chemistry Continues". Erowid Online Library. p. 11. Retrieved 15 November 2013.
↑ , "Method of Treating Mental Depression"
Alexander Shulgin; Ann Shulgin (1997). ""Part 2, The Chemistry Continues: #11, a-ET: Alpha-Ethyltryptamine; Indole,3-(2-Aminobutyl); Tryptamine,Alpha-Ethyl; 3-(2-Aminobutyl)Indole; Monase," part v, "EXTENSIONS AND COMMENTARY."" (Book). Tryptamines i Have Known and Loved: The Continuation, (1st. ed.). Berkeley, CA: Transform Press, ©1997. ISBN 978-0-9630096-9-2. Retrieved 15 November 2013. This base, a-ET or etryptamine, was a promising anti-depressant, explored clinically as the acetate salt by Upjohn under the name of Monase. Its central stimulant activity is probably not due to its monoamineoxidase inhibition activity, but appears to stem from its structural relationship to the indolic psychedelics. It was withdrawn from potential commercial use with the appearance of an unacceptable incidence of a medical condition known as agranulocytosis, but the extra mural research into its action, among the lay population, goes on,
Huang XM, Johnson MP, Nichols DE (July 1991). "Reduction in brain serotonin markers by alpha-ethyltryptamine (Monase)". European Journal of Pharmacology. 200 (1): 187–190. doi:10.1016/0014-2999(91)90686-K. PMID 1722753.

پیوند به بیرون

[1] ""Erowid AET (alpha-ethyltryptamine) Vault"".

[2] Alexander Shulgin; Ann Shulgin. "#11, a-ET: Alpha-Ethyltryptamine; Indole,3-(2-Aminobutyl); Tryptamine,Alpha-Ethyl; 3-(2-Aminobutyl)Indole; Monase,". "Tryptamines i Have Known And Loved: The Continuation", Part 2, "The Chemistry Continues". Erowid Online Library. p. 11. Retrieved 15 November 2013.

[3] , "Method of Treating Mental Depression"

[tihkalbook-4] Alexander Shulgin; Ann Shulgin (1997). ""Part 2, The Chemistry Continues: #11, a-ET: Alpha-Ethyltryptamine; Indole,3-(2-Aminobutyl); Tryptamine,Alpha-Ethyl; 3-(2-Aminobutyl)Indole; Monase," part v, "EXTENSIONS AND COMMENTARY."" (Book). Tryptamines i Have Known and Loved: The Continuation, (1st. ed.). Berkeley, CA: Transform Press, ©1997. ISBN 978-0-9630096-9-2. Retrieved 15 November 2013. This base, a-ET or etryptamine, was a promising anti-depressant, explored clinically as the acetate salt by Upjohn under the name of Monase. Its central stimulant activity is probably not due to its monoamineoxidase inhibition activity, but appears to stem from its structural relationship to the indolic psychedelics. It was withdrawn from potential commercial use with the appearance of an unacceptable incidence of a medical condition known as agranulocytosis, but the extra mural research into its action, among the lay population, goes on,

[pmid1722753-5] Huang XM, Johnson MP, Nichols DE (July 1991). "Reduction in brain serotonin markers by alpha-ethyltryptamine (Monase)". European Journal of Pharmacology. 200 (1): 187–190. doi:10.1016/0014-2999(91)90686-K. PMID 1722753.

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